ERα promotes SUMO1 transcription by binding with the ERE and enhances SUMO1-mediated protein SUMOylation in breast cancer

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چکیده

Background: Estrogen plays a crucial role in the tumorigenesis of breast cancer (BC), and epigenetic modification by SUMOylation is essential for development. However, mechanism underlying estrogen’s actions on protein its effect BC development are still incompletely understood.

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ژورنال

عنوان ژورنال: Gland surgery

سال: 2023

ISSN: ['2227-8575', '2227-684X']

DOI: https://doi.org/10.21037/gs-23-39